Anaesthetists in the acute and chronic pain teams are often involved in treating Complex Regional Pain Syndromes. Current\nliterature about the risk factors for the onset of Complex Regional Pain Syndrome Type 1 (CRPS 1) remains sparse. This syndrome\nhas a low prevalence, a highly variable presentation, and no gold standard for diagnosis. In the research setting, the pathogenesis of\nthe syndrome continues to be elusive. There is a growing body of literature that addresses efficacy of a wide range of interventions\nas well as the likely mechanisms that contribute to the onset of CRPS 1. The objective for this systematic search of the literature\nfocuses on determining the potential risk factors for the onset of CRPS 1. Eligible articles were analysed, dated 1996 to April 2014,\nand potential risk factors for the onset of CRPS 1 were identified from 10 prospective and 6 retrospective studies. Potential risk\nfactors for the onset of CRPS 1 were found to include being female, particularly post menopausal female, ankle dislocation or in traarticular\nfracture, immobilisation, and a report of higher than usual levels of pain in the early phases of trauma. It is not possible\nto draw definite conclusions as this evidence is heterogeneous and of mixed quality, relevance, and weighting strength against bias\nand has not been confirmed across multiple trials or in homogenous studies.
Loading....